4th UpDate on Hepatology Course, Bucharest 6th-7th April 2017 

Hepatology 2017 – A panoramic view

6 April 2017

8.00-9.45 Registration & Welcome

9.50-10.00 Introduction: Liana Gheorghe

10.00-11.30 Challenging issues in hepatitis B

Chair: Ferruccio Bonino, Mircea Diculescu

10.00-10.25 How to manage HBV infected patients in 2017?
Dana Dobru, Targu Mures, Romania
10.25-10.45 Treating/preventing HBV infection in special groups
Adrian Goldis, Timisoara, Romania
10.45-11.05 Long-term impact of antiviral therapy in chronic hepatitis B
Marcel Tantau, Cluj-Napoca, Romania

11.05-12.45 Alcoholic and non-alcoholic liver disease

Chair: Vlad Ratziu, Oliviu Pascu

11.05-11.30 Old and new biomarkers for NASH
Mona Munteanu, Paris, France
11.30-11.55 The impact of new multi-parametric measures of fatty liver by ultrasound and magnetic resonance in clinical practice
Ferrucio Bonino, Pisa, Italy
11.55-12.20 What is the current medical management of NASH and future perspectives?
Ioan Sporea, Timisoara, Romania
12.20-12.45 Treatment of alcoholic hepatitis
Vlad Ratziu, Paris, France

12.45 – 13.15 Satellite Symposium BMS

Benefits of long-term therapy with Baraclude in chronic hepatits B
Speaker: Liana Gheorghe, Bucharest, Romania

13.15-14.15 Lunch

14.15-15.55 Challenging issues in hepatitis C

Chair: Nancy Reau, Ioan Sporea

14.15-14.40 HCV therapy of GT-1 patients now and in the future. Strategies for  simplification
Speranta Iacob, Bucharest, Romania
14.40-15.05  Treatment of HCV special populations: decompensated cirrhosis and chronic kidney disease
Susanne Beckebaum, Muenster, Germany
15.05-15.30 Impact of therapy on hepatic and extrahepatic manifestation of chronic HCV infection
Nancy Reau, Chicago, USA
15.30-15.55 Hepatocellular carcinoma in patients with HCV liver cirrhosis treated with direct-acting antivirals (DAAs)
Liana Gheorghe, Bucharest, Romania

16.00 -16.30 Coffee Break and Poster Viewing

16.30-17.30 Satellite Symposium AbbVie

Viekirax+Exviera: Clinical experience changes HCV horizon in Romania
Speakers: Prof. Liana Gheorghe (Bucharest, Romania)

17.30-18.30 Parallel Case-based Workshops

Workshop 1: Management of chronic hepatitis C in DAAs era
Chair: Carol Stanciu, Susanne Beckebaum:
Presenters: Susanne Beckebaum, Speranta Iacob, Ana Maria Sangeap
Failure to DAA therapy – how to deal with it following liver transplantation?
De novo HCC following 3D antiviral therapy and SVR in a patient with HCV genotype 1b liver cirrhosis
A case of reversible portal vein thrombosis in a patient with HCV-related cirrhosis and SVR after antiviral treatment

Workshop 2: Special issues in liver cirrhosis
Chair: Cristian Gheorghe, Ferrucio Bonino
Presenters: Corina Pop, Ciprian Brisc, Bogdan Procopet
A case of Primary Biliary Cirrhosis with portal thrombosis and bleeding gastric varices
Severe decompensation: liver cirrhosis vs alcoholic hepatitis
A fatal case of variceal bleeding

Workshop 3: Alcoholic & non-alcoholic fatty liver disease
Chair: Ioan Sporea, Vlad Ratziu
Presenters: Roxana Sirli, Corina Pietrareanu
A simple case of non-alcoholic steato-hepatitis?
A case of acute on chronic alcoholic liver disease referred for liver transplantation

19.00 Dinner


7 April 2017

8.30-10.30 Hepatocellular carcinoma

Chair: Patrizia Burra, MarkusPeck-Radosavljevic

8.30-8.50 Combination and dynamics of serum biomarkers to personalized surveillance, diagnosis and management of hepatocellular carcinoma
Maurizia Brunetto, Pisa, Italy
8.50-9.10 Diagnosis of hepatocellular carcinoma by imaging : How can we improve accuracy?
Ioana Lupescu, Bucharest, Romania
9.10-9.30 Radiofrequency ablation: who should be treated, how to be done and response evaluation
Zeno Sparchez, Cluj-Napoca, Romania
9.30-9.50 Transarterial chemoembolization:  who should be treated, how to be done and response evaluation
Mugur Grasu, Bucharest,  Romania
9.50-10.10 Transplantation for hepatocellular carcinoma
Patrizia Burra, Padova, Italy
10.10-10.30 Systemic therapy and immunotherapy for advanced hepatocellular carcinoma
Markus Peck-Radosavljevic, Austria

10.30-11.00 Coffee Break and Poster Viewing

11.00-12.00 Special issues in cirrhosis

Chair: Vito Cicinnati, Cristian Gheorghe

11.00-11.20 Acute on chronic liver disease
Anca Trifan, Iasi, Romania
11.20-11.40  Use of betablockers in decompensated cirrhosis
Cristina Cijevschi, Catalina Mihai, Iasi, Romania
11.40-12.00 Cirrhotic coagulopathy: practical aspects
Dana Tomescu, Bucharest, Romania

12.00 – 13.00 Satellite Symposium MSD

Power through Confidence and Simplicity
Speakers: Prof. Liana Gheorghe (Bucharest, Romania), Prof. Daniela Dobru ( Tg. Mures )

13.00 – 14.00 Lunch

14.00-15.00 Satellite Symposium Gilead

Management of HCV patients with advanced cirrhosis
Speakers: Prof. Marina Berenguer (Valencia, Spain), Prof. Liana Gheorghe (Bucharest, Romania)

15.00-16.30 Original Research Forum

Chair: Costica Aloman, Razvan Iacob

15.00-15.20  Arguments for hepatocyte reprogramming during advanced liver fibrosis – background for hepatocarcinogenesis
Razvan Iacob, Bucharest, Romania
15.20-15.40 Targeting mononuclear phagocytes development in alcoholic liver injury: pathological and immunological pathways
Costica Aloman, Chicago, USA
15.40-15.55 The metabolic profile of decompensation in patients with cirrhosis
Bogdan Procopet, Cluj-Napoca, Romania
15.55-16.10 The role of combined liver and spleen elastometry for the prediction of the response to therapy in severe alcoholic hepatitis
Horia Stefanescu, Cluj-Napoca, Romania
16.10-16.30 Early-TIPS improves survival in high-risk variceal bleeders Results of a multicenter variceal bleeding observational study
Virginia Hernandez Gea, Barcelona, Spain

16.30 -17.00 Coffee break

17.00 – 17.30 Satellite Symposium Alfa Wassermann

Gut Dysbiosis and Inflammation in Cirrhosis and Hepatic Encephalopathy: Role for Microbiota-directed Therapies
Speaker: Carmelo Scarpignato, Parma,  Italy

17.30 -18.30 Autoimmune and genetic liver disease

Chair:  Susanne Beckebaum, Corina Pop

17.30-17.50 Management of autoimmune liver disease in 2017
Vito Cicinnati, Muenster, Germany
17.50-18.10 Management of cholestatic liver diseases in 2017
Iulia Simionov, Bucharest, Romania
18.10-18.30  Wilson disease: from genetics to therapy
Hartmut Schmidt, Muenster, Germany

18.30 Closing and Poster Awards